The Great O'Malley

Pat O'Brien

James Aloysius 'Jim' / 'Jimmy' O'Malley

Sybil Jason

Barbara 'Babs' Phillips

Humphrey Bogart

John Philips

Ann Sheridan

Judy Nolan

Frieda Inescort

Mrs. Philips

Donald Crisp

Police Captain Cromwell

Henry O'Neill

Defense Attorney

Craig Reynolds

Motorist Honking Horn

Hobart Cavanaugh

Reporter Pinky Holden

Gordon Hart

Doctor Attending O'Malley

Mary Gordon

Mrs. O'Malley

Mabel Colcord

Mrs. Flaherty

Frank Sheridan

Father Patrick

Lillian Harmer

Miss Taylor

Delmar Watson

Tubby

Frank Reicher

Dr. Larson

Joseph Allen Sr.

Warden (uncredited)

Granville Bates

Jake - Bar Proprietor (uncredited)